Wednesday, April 28, 2021

Amphetamines

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Amphetamines


Amphetamines stimulate the central nervous system and belong to a group of drugs called psychostimulants. Messages going to and from the brain to the body are sped up with the use of this drug. It is sold illegally and are found in powder, tablet, capsules, crystals, or red liquid form. One can inject it, inhale it, swallow it, or even smoke it. There are many terms used to refer to amphetamines speed, wake ups, jollies, dexies, etc. However, it is most commonly referred to as "speed." Quite a few uses have come about for this drug. For the majority of amphetamine users, it is used as a means of "staying awake." It has been seen to be quite popular among students and party goers use it to get a "high" and dance all night. It basically allows a person to stay up a very long time and improve their daily performance. Such things as work, sports, and other activities become easier while on this drug because it increases a person's endurance. It also increases talkativeness, breathing rate, heart rate, and blood pressure. Users tend to feel energetic and full of confidence while under it. It gives them a huge sense of well being therefore, increasing the chances of that person using it again. Amphetamines also reduce one's appetite, makes them experience hallucinations and repeating their actions.


Now, if one takes a large dose, there are a plethora of effects it can have on them. Many have experienced high fevers, headaches, sweating, dry mouth, paleness, blurred vision, loss of coordination, and even irregular heartbeats. Users have also collapsed while under this drug. Since amphetamines are sold illegally, they are more than often found in impure states. This means that they possibly contain sugar, glucose, bi-carb soda, and ephedrine added to them. These substances added to the amphetamine can be very harmful or poisonous to the individual ingesting the drug. Veins can collapse and damage can occur to the heart, liver, brain, and lungs. That is just the general overview of how amphetamines can effect a person.


So, how exactly do amphetamines affect the brain? They act on the pleasure circuit by altering the levels of certain neurotransmitters present in the synapse. It enters nerve terminals by passing directly through nerve cell membranes. It is also carried into the nerve terminals by transporter molecules that normally carry dopamine or norepinephrine from the synapse back into the nerve terminal. Once in the nerve terminal, methamphetamine enters dopamine and norepinephrine containing vesicles and causes the release of these neurotransmitters. Excess dopamine and norepinephrine would normally be chewed up by enzymes in the cell however, amphetamines block this breakdown. The excess neurotransmitters are then carried by transporter molecules out of the neuron and into the synapse. It then causes those feelings of high pleasure and great alertness. The negative effects on the brain include cerebral edema, brain hemorrhage, paranoia, and hallucinations. These effects may even be long lasting or, in some cases, permanent. There is also the high possibility of becoming tolerant to amphetamines as well as dependent. One becomes addicted to the sense of well-being it gives them and the sense of being on top of their daily activities. It helps them tackle things better because of their increased alertness with the use of this drug. They cannot seem to let go of how it makes them feel and so therefore, their addiction is purely psychological. To beat the addiction one would need to stay off the drug in order for their body to become accustomed to functioning without it. While they are off the drug they will experience withdrawals. Some symptoms include hunger, extreme fatigue, anxiety, irritability, and depression. Past users found going to group therapy allowed them to defeat their addiction. Others sought out counseling techniques as well as medicines to alleviate withdrawal symptoms. Through motivation and confidence, those addicted to amphetamines have been able to recover and attempt to live a healthy lifestyle.


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